Dario Xavier Jimenez Acosta
Enrique Garces Hospital, Ecuador
Title: Choosing the best dialysis treatment for critically ill patients with sepsis in a developing country
Biography
Biography: Dario Xavier Jimenez Acosta
Abstract
Introduction: AKI is a serious problem in critically ill patients with sepsis; in Ecuador it has a prevalence of 10% and a high undocumented mortality rate. The type of renal replacement therapy used is also very discussed in countries with several options. In Ecuador there are no continuous treatments available for patients. Objective: The aim was demonstrate advantages in AKI treatment between hemodiafiltration with an own scheme vs. intermittent hemodialysis. The primary outcomes were mortality, vasoactive drugs, mechanical ventilation dependence and time of ICU stay. Results: Cohort and tracing study in ICUs in patients with sepsis and AKI. Two groups undergoing treatment for intermittent hemodialysis GA (n30) vs. hemodiafiltration GB (n21). 51 patients were observed. The general mortality was 54.9%, (63% GA vs. 42.8% GB p=0.09) had no statistical significance. Apache and SOFA index media were 26 and 11 respectively without statistical significance between both groups (p=0.65). Time ICU stay (GA: 18.33, GB: 10.76 p=0.027) vasoactive drugs dependence (GA: 9.77, GB: 4.19 p=0.089) MV dependence (GA: 12.13, GB: 6.62 p=0,036). Conclusions: HDF showed benefits in vasoactive drugs, MV dependence and ICU stay. The mortality was not statistically significative. We recommended HDF with our scheme for AKI treatment in critically ill patients with sepsis independent of mortality results.