K S Nayak
Deccan Institute of Nephrology and Renal Transplantation, India
Title: Treatment of Chronic Kidney Disease patients with ketoanalogue supplemented low protein diet and ketonalogue supplemented very low protein diet
Biography
Biography: K S Nayak
Abstract
Introduction: A low protein diet (0.6 G/Kg BW) and a very low protein diet(0.3 G/Kg BW) supplemented with ketoanalogues have been shown to be even more efficacious in further improving the benefits of a low protein diet in CKD patients. Material & Methods: 164 adult patients with Stage 3 to Stage 5 (Predialysis) were initiated on ketoanalogue supplemented low protein diet (sLPD) after informed consent and the necessary Institutional Ethics Committee approvals. Based on their affordability, 116 patients randomly were assigned to the sLPD group whereby they received 0.6gm/kg BW of dietary proteins supplemented by ketoanalogues (Renolog: La RenonHealthCare, Ahmedabad, India) at a dosage of one tablet per 10 Kg body weight. 48 patients received 0.3 gm/kg BW supplemented by Renologat a dose of one tablet per 5 Kg body weight. Renal, metabolic, nutritional parameters and anthropometric analysis were done in both groups at the start of the study, at the end of six months and at the end of twelve months of treatment. Results: Total number of patients in the study group were 164 of which 116 were on sLPD and 48 were on sVLPD regimen. Period of study was twelve months. The number of Renolog tablets consumed per day in the sLPD group was 6.10+_1.03 and 12.19 +_1.83 in the sVLPD group. The difference was statistically significant (p <0.001 ).